SCHEMBL8034346

SCHEMBL8034346

CC(C)CC(C=CCO)NC(=O)OC(C)(C)C

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CTSK P43235 11/20 0.49
CTSL P07711 2/20 0.48
CTSB P07858 1/20 0.48
CTSS P25774 1/20 0.48
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CAPN1 P07384 1/20 0.45
REN P00797 1/20 0.40
CYP2D6 P10635 1/20 0.39
GAA P10253 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
AAK1 Q2M2I8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10545929 1.00 CTSK (0.49) CTSKCTSLCTSBCTSSCA1
SCHEMBL1922633 0.88 CTSK (0.47) CTSKCTSLCTSBCTSSCA1
SCHEMBL1922636 0.88 CTSK (0.47) CTSKCTSLCTSBCTSSCA1
SCHEMBL1922635 0.88 CTSK (0.47) CTSKCTSLCTSBCTSSCA1
SCHEMBL1922634 0.88 CTSK (0.47) CTSKCTSLCTSBCTSSCA1
SCHEMBL9556266 0.88 CTSK (0.52) CTSKCTSLCTSBCTSSCA1
SCHEMBL7435372 0.88 CTSK (0.52) CTSKCTSLCTSBCTSSCA1
SCHEMBL7435374 0.88 CTSK (0.52) CTSKCTSLCTSBCTSSCA1
SCHEMBL16480228 0.88 CTSK (0.49) CTSKCTSLCTSBCTSSCA1
SCHEMBL7435376 0.88 CTSK (0.52) CTSKCTSLCTSBCTSSCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6127546-A Process for the preparation of oxazoline compound DONG KOOK PHARMACEUTICAL CO., LTD. (KR) 2000-10-03 US disclosed