SCHEMBL7435452

SCHEMBL7435452

NCC(=O)c1cccc2ccccc12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.67
NR4A1 P22736 1/20 0.59
NR4A2 P43354 1/20 0.59
NR4A3 Q92570 1/20 0.59
ALDH1A1 P00352 5/20 0.57
MAPT P10636 4/20 0.57
HPGD P15428 4/20 0.57
KDM4E B2RXH2 4/20 0.57
MEN1 O00255 2/20 0.57
GMNN O75496 2/20 0.57
LMNA P02545 2/20 0.57
POLB P06746 2/20 0.57
MAPK1 P28482 2/20 0.57
BLM P54132 2/20 0.57
PMP22 Q01453 2/20 0.57
KMT2A Q03164 2/20 0.57
NPSR1 Q6W5P4 2/20 0.57
CMKLR1 Q99788 2/20 0.57
TDP1 Q9NUW8 2/20 0.57
TP53 P04637 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29391682 0.98 PTPN1 (0.65) PTPN1NR4A1NR4A2NR4A3ALDH1A1
SCHEMBL6008188 0.86 ALDH1A1 (0.65) PTPN1NR4A1NR4A2NR4A3ALDH1A1
SCHEMBL29457006 0.83 PTPN1 (0.71) PTPN1NR4A1NR4A2NR4A3ALDH1A1
SCHEMBL5857951 0.83 PTPN1 (0.71) PTPN1NR4A1NR4A2NR4A3ALDH1A1
SCHEMBL11713079 0.82 PTPN1 (0.69) PTPN1NR4A1NR4A2NR4A3ALDH1A1
SCHEMBL30375866 0.82 PTPN1 (0.69) PTPN1NR4A1NR4A2NR4A3ALDH1A1
SCHEMBL1448941 0.82 PTPN1 (0.69) PTPN1NR4A1NR4A2NR4A3ALDH1A1
SCHEMBL4707024 0.81 PTPN1 (0.62) PTPN1NR4A1NR4A2NR4A3ALDH1A1
SCHEMBL10358075 0.81 ALDH1A1 (0.63) PTPN1NR4A1NR4A2NR4A3ALDH1A1
SCHEMBL27533876 0.80 ALDH1A1 (0.46) PTPN1ALDH1A1MAPTHPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106894064-A A kind of special acid electroplated zinc nickel alloy electrolyte of transformer case casting 南通市海王电气有限公司 2017-06-27 CN claimed
US-11957766-B2 HNQO1-activatable fluorescent probe for imaging cancer cells in-vitro and in-vivo TEXAS TECH UNIVERSITY SYSTEM (US) 2024-04-16 US disclosed
US-20210154330-A1 HNQO1-ACTIVATABLE FLUORESCENT PROBE FOR IMAGING CANCER CELLS IN-VITRO AND IN-VIVO TEXAS TECH UNIVERSITY SYSTEM 2021-05-27 US disclosed
CN-106894064-A A kind of special acid electroplated zinc nickel alloy electrolyte of transformer case casting 南通市海王电气有限公司 2017-06-27 CN disclosed
CN-104694983-B A kind of acid electroplating zinc-nickel alloy electrolyte and preparation method thereof and its electro-plating method 南通创源电化学科技有限公司 2017-03-08 CN disclosed
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
EP-0685489-A2 Tripeptide antithrombotic agents ELI LILLY AND COMPANY (US) 1995-12-06 EP disclosed
US-5430023-A Tripeptide antithrombotic agents ELI LILLY AND COMPANY (US) 1995-07-04 US disclosed
US-5252566-A Antithrombotic agents ELI LILLY AND COMPANY (US) 1993-10-12 US disclosed
EP-0542525-A2 Antithrombotic agents ELI LILLY AND COMPANY (US) 1993-05-19 EP disclosed
EP-0479489-A2 Tripeptide antithrombotic agents ELI LILLY AND COMPANY (US) 1992-04-08 EP disclosed
CN-1006386-B PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER SHINETSU CHEM IND CO (JP) 1990-01-10 CN disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
CN-85107531-A Process for producing vinyl chloride polymer 1987-01-21 CN disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210154330-A1 HNQO1-ACTIVATABLE FLUORESCENT PROBE FOR IMAGING CANCER CELLS IN-VITRO AND IN-VIVO NQO1, NQO2, NDUFA1 PTPN1 4045/4885NR4A1 2339/4885NR4A2 2205/4885
US-11957766-B2 HNQO1-activatable fluorescent probe for imaging cancer cells in-vitro and in-vivo NQO1, NQO2, NDUFA1 PTPN1 4045/4885NR4A1 2339/4885NR4A2 2205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.