Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 2/20 | 0.50 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 2/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9160311 | 0.83 | ITGA4 (0.52) | ITGA4ITGB7ATMPOLBMAPT | |
| SCHEMBL7279136 | 0.81 | PPARA (0.53) | ITGA4ITGB7CTSSKLK5 | |
| SCHEMBL6288293 | 0.81 | ITGA4 (0.51) | ITGA4ITGB7ATMPOLBMAPT | |
| SCHEMBL21601599 | 0.81 | ITGA4 (0.51) | ITGA4ITGB7ATMPOLBMAPT | |
| SCHEMBL1595571 | 0.81 | ITGA4 (0.51) | ITGA4ITGB7ATMPOLBMAPT | |
| SCHEMBL13108100 | 0.81 | ITGA4 (0.51) | ITGA4ITGB7ATMPOLBMAPT | |
| SCHEMBL487423 | 0.81 | ITGA4 (0.51) | ITGA4ITGB7ATMPOLBMAPT | |
| SCHEMBL4909735 | 0.81 | ITGA4 (0.51) | ITGA4ITGB7ATMPOLBMAPT | |
| SCHEMBL1595565 | 0.81 | ITGA4 (0.51) | ITGA4ITGB7ATMPOLBMAPT | |
| SCHEMBL30759366 | 0.81 | ITGA4 (0.51) | ITGA4ITGB7ATMPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312826-A | Dicarboxylic acids with hypotensive agents and cardiovascular disorders | TANABE SEIYAKU CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| EP-0519738-A1 | Dicarboxylic acid derivatives and process for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1992-12-23 | — | — | EP | disclosed |