Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KLK7 | P49862 | 2/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487462 | 0.84 | PPARA (0.54) | PPARACA1CA2CA7CA9 | |
| SCHEMBL23541264 | 0.84 | PPARA (0.54) | PPARACA1CA2CA7CA9 | |
| SCHEMBL3732892 | 0.84 | PPARA (0.57) | PPARACA1CA2CA7CA9 | |
| SCHEMBL487460 | 0.84 | PPARA (0.54) | PPARACA1CA2CA7CA9 | |
| SCHEMBL4220523 | 0.82 | SLC1A1 (0.54) | PPARACA1CA2CA7CA9 | |
| SCHEMBL7338978 | 0.82 | SLC1A1 (0.54) | PPARACA1CA2CA7CA9 | |
| SCHEMBL27846599 | 0.82 | PPARA (0.53) | PPARACA1CA2CA7CA9 | |
| SCHEMBL9025179 | 0.82 | PPARA (0.53) | PPARACA1CA2CA7CA9 | |
| SCHEMBL2584804 | 0.82 | SLC1A1 (0.54) | PPARACA1CA2CA7CA9 | |
| SCHEMBL7435761 | 0.81 | ITGA4 (0.50) | CTSSKLK5ITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | disclosed |