Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.55 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CCKBR | P32239 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.42 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.42 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.42 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2425275 | 0.96 | MAPK9 (0.53) | MAPK9MAPK10KMT2AMEN1BCL2 | |
| SCHEMBL2420177 | 0.94 | MAPK9 (0.60) | MAPK9MAPK10KMT2AMEN1BCL2 | |
| SCHEMBL7894669 | 0.90 | MAPK9 (0.59) | MAPK9MAPK10KMT2AMEN1BCL2 | |
| SCHEMBL7894704 | 0.87 | MAPK9 (0.55) | MAPK9MAPK10KMT2AMEN1MAPT | |
| SCHEMBL7894671 | 0.86 | MEN1 (0.58) | MAPK9MAPK10KMT2AMEN1MAPT | |
| SCHEMBL2421411 | 0.86 | MAPK9 (0.53) | MAPK9MAPK10KMT2AMEN1BCL2 | |
| SCHEMBL7894689 | 0.86 | MAPK9 (0.55) | MAPK9MAPK10KMT2AMEN1MAPT | |
| SCHEMBL3479891 | 0.85 | MAPK9 (0.53) | MAPK9MAPK10KMT2AMEN1BCL2 | |
| SCHEMBL3480236 | 0.85 | MAPK9 (0.57) | MAPK9MAPK10KMT2AMEN1BCL2 | |
| SCHEMBL6431701 | 0.84 | MAPK9 (0.59) | MAPK9MAPK10KMT2AMEN1BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218374-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | Applied Research Systems ARS Holding N.V. (AN) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001023378-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-04-05 | — | — | WO | disclosed |