Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4221454 | 0.84 | ALPG (0.51) | L3MBTL1KMT2AAPPGAASMN1; SMN2 | |
| SCHEMBL5917702 | 0.84 | KMT2A (0.50) | L3MBTL1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL20616667 | 0.80 | TRPM8 (0.59) | KMT2ASMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL30514942 | 0.79 | KMT2A (0.46) | L3MBTL1KMT2AAPPGAASMN1; SMN2 | |
| SCHEMBL25335749 | 0.79 | KMT2A (0.46) | L3MBTL1KMT2AAPPGAASMN1; SMN2 | |
| SCHEMBL7679291 | 0.79 | APP (0.52) | L3MBTL1KMT2AAPPGAASMN1; SMN2 | |
| SCHEMBL25337245 | 0.78 | IDO1 (0.49) | L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL20616624 | 0.78 | KMT2A (0.73) | KMT2AGAASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL5917726 | 0.77 | KMT2A (0.44) | L3MBTL1KMT2AAPPGAASMN1; SMN2 | |
| SCHEMBL7829437 | 0.76 | APP (0.49) | L3MBTL1KMT2AAPPGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207677-B1 | ADMINISERING SIGMA RECEPTOR BINDING PIPERIDINE DERIVATIVE FOR TREATING ANXIETY, EPILEPSY, CONVULSION, MOVEMENT DISORDER, AMNESIA | H. LUNDBECK A/S (DK) | 2001-03-27 | — | — | US | disclosed |
| US-6031099-A | Piperidine derivates having anxiolytic effect | H. LUNDBECK A/S (DK) | 2000-02-29 | — | — | US | disclosed |
| US-5807871-A | PSYCHOLOGICAL DISORDERS, ALZHEIMER OR PARKINSON DISEASE | H. LUNDBECK A/S (DK) | 1998-09-15 | — | — | US | disclosed |
| EP-0593511-B1 | PIPERIDINE DERIVATES HAVING ANXIOLYTIC EFFECT | LUNDBECK & CO AS H (DK) | 1998-09-02 | — | — | EP | disclosed |
| EP-0859004-A1 | Piperidine derivatives having anxiolytic effect | H. LUNDBECK A/S (DK) | 1998-08-19 | — | — | EP | disclosed |
| EP-0853085-A1 | Piperidine derivatives having anxiolytic effect | H. LUNDBECK A/S (DK) | 1998-07-15 | — | — | EP | disclosed |
| US-5665725-A | Piperidine derivatives having anxiolytic effect | Lundbeck, H. (DK) | 1997-09-09 | — | — | US | disclosed |
| EP-0518805-A1 | Piperidine derivatives | H. LUNDBECK A/S (DK) | 1992-12-16 | — | — | EP | disclosed |