Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 14/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5917702 | 0.93 | KMT2A (0.50) | IDO1KMT2AL3MBTL1ALDH1A1HDAC3 | |
| SCHEMBL4221454 | 0.79 | ALPG (0.51) | KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL5812872 | 0.79 | FAAH (0.57) | IDO1KMT2AL3MBTL1ALDH1A1HDAC3 | |
| SCHEMBL7435969 | 0.78 | L3MBTL1 (0.51) | KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL20270062 | 0.77 | FAAH (0.46) | IDO1KMT2AL3MBTL1ALDH1A1HDAC3 | |
| SCHEMBL8260350 | 0.76 | FAAH (0.44) | KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL30514942 | 0.75 | KMT2A (0.46) | KMT2AL3MBTL1ALDH1A1HDAC3HDAC4 | |
| SCHEMBL25335749 | 0.75 | KMT2A (0.46) | KMT2AL3MBTL1ALDH1A1HDAC3HDAC4 | |
| SCHEMBL1175533 | 0.72 | KMT2A (0.82) | IDO1KMT2AALDH1A1HDAC3HDAC4 | |
| SCHEMBL5917726 | 0.72 | KMT2A (0.44) | IDO1KMT2AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146989-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |