Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.41 |
| ▸ | ARG2 | P78540 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 3/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.34 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436145 | 1.00 | GRIK1 (0.41) | GRIK1GRIK2ARG2LTA4HSLC1A1 | |
| SCHEMBL7430683 | 0.89 | GRIK1 (0.39) | GRIK1GRIK2LTA4HSLC1A1P2RY10 | |
| SCHEMBL7430691 | 0.89 | GRIK1 (0.39) | GRIK1GRIK2LTA4HSLC1A1P2RY10 | |
| SCHEMBL7433486 | 0.87 | P2RY10 (0.40) | GRIK1GRIK2LTA4HP2RY10GPR174 | |
| SCHEMBL7433487 | 0.87 | P2RY10 (0.40) | GRIK1GRIK2LTA4HP2RY10GPR174 | |
| SCHEMBL13662314 | 0.80 | P2RY10 (0.36) | ARG2LTA4HSLC1A1P2RY10GPR174 | |
| SCHEMBL11776470 | 0.79 | SMN1; SMN2 (0.42) | LTA4HSLC1A1CA1CA2SMN1; SMN2 | |
| SCHEMBL15723449 | 0.78 | ALDH1A1 (0.40) | LTA4HCA1CA2SMN1; SMN2TSHR | |
| SCHEMBL7274493 | 0.78 | ALDH1A1 (0.40) | LTA4HCA1CA2SMN1; SMN2TSHR | |
| SCHEMBL28363798 | 0.78 | PPARG (0.38) | PPARGPPARDPPARACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4973585-A | INHIBITORS OF ANGIOTENSIN CONVERTING ENZYME | MERRELL DOW PHARMACEUTICALS (US) | 1990-11-27 | — | — | US | disclosed |
| EP-0249223-A2 | Novel antihypertensive agent | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-12-16 | — | — | EP | disclosed |