SCHEMBL7436153

SCHEMBL7436153

CCCCCOC(=O)C(CNC(=O)[C@@H]1CCCN(C(=O)CCC2CCN(C(=O)OC(C)(C)C)CC2)C1)NC(C)=O

nearest known ligand 0.45

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 19/20 0.45
ITGA2B P08514 19/20 0.45
F2R P25116 7/20 0.45
BCHE P06276 1/20 0.41
ACHE P22303 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7496481 0.91 ITGB3 (0.48) ITGB3ITGA2BF2R
SCHEMBL6936430 0.88 ITGB3 (0.55) ITGB3ITGA2BF2R
SCHEMBL6937901 0.88 ITGB3 (0.55) ITGB3ITGA2BF2R
SCHEMBL7501005 0.87 ITGB3 (0.45) ITGB3ITGA2BF2RBCHEACHE
Hydrochloric Acid SCHEMBL7446360 0.87 ITGB3 (0.59) ITGB3ITGA2BF2R
SCHEMBL7506666 0.87 ITGB3 (0.44) ITGB3ITGA2BF2RBCHEACHE
SCHEMBL7436163 0.86 ITGB3 (0.46) ITGB3ITGA2BF2R
SCHEMBL7502053 0.85 ITGB3 (0.45) ITGB3ITGA2BF2R
SCHEMBL7501010 0.85 ITGB3 (0.48) ITGB3ITGA2BF2RBCHEACHE
SCHEMBL7506668 0.84 ITGB3 (0.47) ITGB3ITGA2BF2RBCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6384028-B1 TREATMENT OF CARDIOVASCULAR DISORDERS, ANTICOAGULANTS AND VALVE REPLACEMENT FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-05-07 US disclosed
WO-1996029309-A1 N-ACYLPIPERIDINYLCARBONYLAMINOCARBOXYLIC ACIDS AND THEIR USE AS GLYCOPROTEIN IIB/IIa ANTAGONISTS AND FIBRINOGEN-BLOOD PLATELETS BINDING INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-09-26 WO disclosed