Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.62 |
| ▸ | CTSL | P07711 | 2/20 | 0.62 |
| ▸ | CTSS | P25774 | 2/20 | 0.62 |
| ▸ | MME | P08473 | 1/20 | 0.55 |
| ▸ | ECE1 | P42892 | 1/20 | 0.55 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 3/20 | 0.52 |
| ▸ | CTSD | P07339 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436214 | 1.00 | CTSK (0.62) | CTSKCTSLCTSSMMEECE1 | |
| SCHEMBL7434549 | 0.94 | CTSK (0.62) | CTSKCTSLCTSSCAPN1ATM | |
| SCHEMBL7434546 | 0.94 | CTSK (0.62) | CTSKCTSLCTSSCAPN1ATM | |
| SCHEMBL7438354 | 0.93 | MME (0.62) | CTSKCTSLCTSSMMEECE1 | |
| SCHEMBL7438341 | 0.93 | MME (0.62) | CTSKCTSLCTSSMMEECE1 | |
| SCHEMBL7430795 | 0.91 | MME (0.54) | CTSKCTSLCTSSMMEECE1 | |
| SCHEMBL7436684 | 0.91 | MME (0.58) | CTSKCTSLMMEECE1CAPN1 | |
| SCHEMBL7442432 | 0.91 | CTSK (0.51) | CTSKCTSLCTSSMMEECE1 | |
| SCHEMBL7427743 | 0.89 | MME (0.56) | CTSKCTSSMMEECE1CAPN1 | |
| SCHEMBL9509483 | 0.89 | MME (0.55) | CTSKCTSLCTSSMMEECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4453003-A | ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS | UMEZAWA HAMAO (JP) | 1984-06-05 | — | — | US | disclosed |
| US-4391986-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediates therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-07-05 | — | — | US | disclosed |
| US-4281180-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediated therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-07-28 | — | — | US | disclosed |