Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.58 |
| ▸ | ECE1 | P42892 | 1/20 | 0.58 |
| ▸ | CTSK | P43235 | 3/20 | 0.57 |
| ▸ | CTSL | P07711 | 1/20 | 0.57 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.56 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438341 | 0.96 | MME (0.62) | MMEECE1CTSKCTSLCAPN1 | |
| SCHEMBL7438354 | 0.96 | MME (0.62) | MMEECE1CTSKCTSLCAPN1 | |
| SCHEMBL7427743 | 0.92 | MME (0.56) | MMEECE1CTSKCAPN1PSMB1 | |
| SCHEMBL7436214 | 0.91 | CTSK (0.62) | MMEECE1CTSKCTSLCAPN1 | |
| SCHEMBL9510605 | 0.91 | MME (0.55) | MMEECE1CTSKCTSLCAPN1 | |
| SCHEMBL7436209 | 0.91 | CTSK (0.62) | MMEECE1CTSKCTSLCAPN1 | |
| SCHEMBL9509483 | 0.91 | MME (0.55) | MMEECE1CTSKCTSLCAPN1 | |
| SCHEMBL7430795 | 0.90 | MME (0.54) | MMEECE1CTSKCTSLCAPN1 | |
| SCHEMBL10507914 | 0.89 | CTSK (0.60) | MMEECE1CTSKCTSLCAPN1 | |
| SCHEMBL9509435 | 0.89 | MME (0.54) | MMEECE1CTSKCTSLCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4453003-A | ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS | UMEZAWA HAMAO (JP) | 1984-06-05 | — | — | US | disclosed |
| US-4391986-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediates therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-07-05 | — | — | US | disclosed |
| US-4281180-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediated therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-07-28 | — | — | US | disclosed |