Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6057191 | 0.98 | GPR139 (0.53) | GPR139KMT2AACEMAPTALDH1A1 | |
| SCHEMBL18759308 | 0.85 | GPR139 (0.51) | GPR139KMT2AACEMAPTALDH1A1 | |
| SCHEMBL5695631 | 0.83 | GPR139 (0.50) | GPR139KMT2AACEMAPTALDH1A1 | |
| SCHEMBL7897731 | 0.83 | GPR139 (0.50) | GPR139KMT2AACEMAPTALDH1A1 | |
| SCHEMBL1356206 | 0.83 | GPR139 (0.50) | GPR139KMT2AACEMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL643490 | 0.81 | GPR139 (0.49) | GPR139KMT2AACEMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL7450354 | 0.81 | GPR139 (0.49) | GPR139KMT2AACEMAPTALDH1A1 | |
| SCHEMBL29089227 | 0.81 | GPR139 (0.56) | GPR139KMT2AACEMAPTALDH1A1 | |
| SCHEMBL6162834 | 0.81 | GPR139 (0.46) | GPR139KMT2AACEMAPTALDH1A1 | |
| SCHEMBL8307306 | 0.80 | GPR139 (0.48) | GPR139KMT2AACEMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |