Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | SCN1A | P35498 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.54 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 6/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10733487 | 0.89 | MEN1 (0.69) | MEN1LMNACYP2D6HRH1SCN1A | |
| SCHEMBL11683141 | 0.88 | CYP19A1 (0.48) | MEN1LMNACYP2D6HRH1SCN1A | |
| SCHEMBL16291428 | 0.86 | MEN1 (0.56) | MEN1LMNACYP2D6HRH1SCN1A | |
| SCHEMBL3657243 | 0.86 | MEN1 (0.57) | MEN1LMNACYP2D6HRH1SCN1A | |
| SCHEMBL7328353 | 0.82 | CYP2D6 (0.81) | MEN1LMNACYP2D6HRH1SCN1A | |
| SCHEMBL2306732 | 0.81 | MEN1 (0.68) | MEN1LMNACYP2D6HRH1SCN1A | |
| Hydrochloric Acid SCHEMBL7442875 | 0.80 | CYP2D6 (0.66) | MEN1LMNACYP2D6HRH1SCN1A | |
| SCHEMBL10461618 | 0.79 | MEN1 (0.35) | MEN1LMNACYP2D6HRH1SCN1A | |
| Hydrochloric Acid SCHEMBL10459095 | 0.78 | CYP2D6 (0.64) | MEN1LMNACYP2D6HRH1SCN1A | |
| SCHEMBL10460811 | 0.77 | ALDH1A1 (0.52) | MEN1LMNAKMT2ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5070087-A | Aryl(alkyland alkylene)-N-((phenoxy and phenylthio)alkyl) aminoheterocyclics as cardiovascular, anthihistaminic, antisecretory and antiallergy agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1991-12-03 | — | — | US | disclosed |
| US-5063235-A | 4-[(diaryl)hydromethyl]-1-piperidinealkanols and esters and carbamates thereof useful in the treatment of allergic disorders | A. H. ROBINS COMPANY, INC. (US) | 1991-11-05 | — | — | US | disclosed |
| US-5057524-A | Asthma, dermatitis | A. H. ROBINS COMPANY INCORPORATED (US) | 1991-10-15 | — | — | US | disclosed |
| US-4950674-A | Arylalkylheterocyclic amines,N-substituted by aryloxyalkyl group in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1990-08-21 | — | — | US | disclosed |
| US-4886794-A | ANTIHISTAMINES, ANTIALLERGENS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-12-12 | — | — | US | disclosed |
| US-4806560-A | ANTIHISTAMINES AND ANTISEROTONINE AGENTS | SYNTHELABO (FR) | 1989-02-21 | — | — | US | disclosed |