Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NPY2R | P49146 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430849 | 0.90 | PKM (0.60) | ALDH1A1PKMKDM4ELMNAGAA | |
| SCHEMBL7442335 | 0.82 | ALDH1A1 (0.52) | ALDH1A1PKMKDM4EGAAPOLB | |
| SCHEMBL11683141 | 0.81 | CYP19A1 (0.48) | ALDH1A1LMNARAB9ANPY2RMEN1 | |
| SCHEMBL7432420 | 0.78 | ALDH1A1 (0.55) | ALDH1A1PKMKDM4EGAAPOLB | |
| SCHEMBL10460341 | 0.77 | NPY2R (0.55) | ALDH1A1PKMKDM4ELMNANPY2R | |
| SCHEMBL7436247 | 0.77 | MEN1 (0.54) | LMNANPY2RMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9786921 | 0.77 | MEN1 (0.57) | MEN1KMT2A | |
| SCHEMBL10461596 | 0.77 | MEN1 (0.56) | ALDH1A1PKMPOLBNPY2RMEN1 | |
| SCHEMBL10460610 | 0.77 | NPY2R (0.49) | ALDH1A1PKMKDM4EGAAPOLB | |
| SCHEMBL10479198 | 0.76 | MEN1 (0.56) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4950674-A | Arylalkylheterocyclic amines,N-substituted by aryloxyalkyl group in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1990-08-21 | — | — | US | disclosed |