Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443382 | 0.85 | TACR1 (0.53) | MMELMNATP53 | |
| SCHEMBL7438793 | 0.83 | MME (0.59) | MMEALDH1A1 | |
| SCHEMBL7303833 | 0.81 | LMNA (0.58) | LMNATP53HSD17B10ALDH1A1NPC1 | |
| SCHEMBL7307895 | 0.77 | LMNA (0.55) | LMNATP53HSD17B10ALDH1A1NPC1 | |
| SCHEMBL7308841 | 0.74 | LMNA (0.56) | LMNATP53HSD17B10ALDH1A1NPC1 | |
| SCHEMBL7432462 | 0.74 | MME (0.68) | MME | |
| SCHEMBL7308749 | 0.74 | LMNA (0.64) | LMNATP53HSD17B10ALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL7304548 | 0.73 | LMNA (0.62) | LMNATP53HSD17B10ALDH1A1NPC1 | |
| SCHEMBL27751166 | 0.73 | LMNA (0.69) | LMNATP53HSD17B10ALDH1A1NPC1 | |
| SCHEMBL7305542 | 0.72 | LMNA (0.53) | LMNATP53HSD17B10ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312826-A | Dicarboxylic acids with hypotensive agents and cardiovascular disorders | TANABE SEIYAKU CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| EP-0519738-A1 | Dicarboxylic acid derivatives and process for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1992-12-23 | — | — | EP | disclosed |