Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.51 |
| ▸ | CTSK | P43235 | 5/20 | 0.51 |
| ▸ | CTSB | P07858 | 4/20 | 0.51 |
| ▸ | BCL2 | P10415 | 1/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.49 |
| ▸ | YAP1 | P46937 | 2/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436304 | 1.00 | CTSS (0.51) | CTSSCTSKCTSBBCL2SCN9A | |
| SCHEMBL7361331 | 0.91 | BCL2 (0.61) | CTSSCTSKCTSBBCL2SCN9A | |
| SCHEMBL8552202 | 0.85 | BCL2 (0.48) | CTSSCTSKCTSBBCL2SCN9A | |
| Ammonia Solution, Strong SCHEMBL27493136 | 0.84 | BCL2 (0.47) | CTSSCTSKCTSBBCL2SCN9A | |
| SCHEMBL4650144 | 0.83 | PTPN1 (0.64) | CTSSCTSKCTSBBCL2YAP1 | |
| SCHEMBL31407708 | 0.83 | PTPN1 (0.64) | CTSSCTSKCTSBBCL2YAP1 | |
| SCHEMBL2552297 | 0.83 | PTPN1 (0.64) | CTSSCTSKCTSBBCL2YAP1 | |
| SCHEMBL7367771 | 0.83 | BCL2 (0.60) | CTSSCTSKCTSBBCL2SCN9A | |
| SCHEMBL2353801 | 0.81 | KLK5 (0.59) | CTSSCTSKCTSBBCL2YAP1 | |
| SCHEMBL20905733 | 0.81 | PTPN1 (0.55) | CTSSCTSKCTSBBCL2CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4873253-A | Phenylalanine derivative and proteinase inhibitor | Okamoto, Shosuke (JP) | 1989-10-10 | — | — | US | disclosed |
| EP-0284632-A1 | Phenylalanine derivative and proteinase inhibitor | Okamoto, Shosuke (JP) | 1988-10-05 | — | — | EP | disclosed |