Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 2/20 | 0.60 |
| ▸ | YAP1 | P46937 | 5/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.52 |
| ▸ | REN | P00797 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 2/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.49 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.49 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.49 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361331 | 0.92 | BCL2 (0.61) | BCL2YAP1PTPN1HDAC8SCN9A | |
| SCHEMBL7274495 | 0.91 | CTSS (0.60) | SCN9ACTSSCTSLCTSBCTSK | |
| SCHEMBL10421038 | 0.87 | KMT2A (0.58) | BCL2YAP1PSMB10PSMB1PSMB8 | |
| SCHEMBL7283532 | 0.83 | MMP9 (0.69) | BCL2PTPN1HDAC8RENCTSS | |
| SCHEMBL7283537 | 0.83 | MMP9 (0.69) | BCL2PTPN1HDAC8RENCTSS | |
| SCHEMBL7436310 | 0.83 | CTSS (0.51) | BCL2YAP1PTPN1SCN9ACTSS | |
| SCHEMBL7436304 | 0.83 | CTSS (0.51) | BCL2YAP1PTPN1SCN9ACTSS | |
| SCHEMBL5833558 | 0.82 | BCL2 (0.68) | BCL2PTPN1HDAC8RENCTSS | |
| SCHEMBL5833552 | 0.82 | BCL2 (0.68) | BCL2PTPN1HDAC8RENCTSS | |
| SCHEMBL8552202 | 0.82 | BCL2 (0.48) | BCL2YAP1SCN9ACTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4895842-A | Phenylalanine derivative and proteinase inhibitor | SHOSUKE OKAMOTO (JP) | 1990-01-23 | — | — | US | disclosed |
| EP-0217286-A1 | Phenylalanine derivative and proteinase inhibitor | Okamoto, Shosuke (JP) | 1987-04-08 | — | — | EP | disclosed |