Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | STAT6 | P42226 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | GPR183 | P32249 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436371 | 1.00 | MAPT (0.60) | MAPTALDH1A1STAT6TP53HSD17B10 | |
| SCHEMBL26550191 | 0.86 | MAPT (0.56) | MAPTALDH1A1STAT6TP53HSD17B10 | |
| SCHEMBL7431601 | 0.85 | ALDH1A1 (0.59) | MAPTALDH1A1STAT6TP53HSD17B10 | |
| SCHEMBL7431607 | 0.85 | ALDH1A1 (0.59) | MAPTALDH1A1STAT6TP53HSD17B10 | |
| SCHEMBL7440848 | 0.85 | ALDH1A1 (0.66) | MAPTALDH1A1STAT6TP53HSD17B10 | |
| SCHEMBL7440852 | 0.85 | ALDH1A1 (0.66) | MAPTALDH1A1STAT6TP53HSD17B10 | |
| SCHEMBL26550411 | 0.84 | ALDH1A1 (0.55) | MAPTALDH1A1STAT6TP53HSD17B10 | |
| SCHEMBL19051845 | 0.83 | ALDH1A1 (0.57) | MAPTALDH1A1STAT6TP53HSD17B10 | |
| SCHEMBL26550185 | 0.82 | ALDH1A1 (0.53) | MAPTALDH1A1STAT6TP53HSD17B10 | |
| SCHEMBL10339541 | 0.81 | GAA (0.54) | MAPTALDH1A1STAT6TP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |