Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | STAT6 | P42226 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | GPR183 | P32249 | 6/20 | 0.54 |
| ▸ | F3 | P13726 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440848 | 1.00 | ALDH1A1 (0.66) | ALDH1A1MAPTSTAT6TP53HSD17B10 | |
| SCHEMBL26550166 | 0.85 | ALDH1A1 (0.64) | ALDH1A1MAPTSTAT6TP53HSD17B10 | |
| SCHEMBL7436371 | 0.85 | MAPT (0.60) | ALDH1A1MAPTSTAT6TP53HSD17B10 | |
| SCHEMBL7436369 | 0.85 | MAPT (0.60) | ALDH1A1MAPTSTAT6TP53HSD17B10 | |
| SCHEMBL26550191 | 0.82 | MAPT (0.56) | ALDH1A1MAPTSTAT6TP53HSD17B10 | |
| SCHEMBL7431601 | 0.82 | ALDH1A1 (0.59) | ALDH1A1MAPTSTAT6TP53HSD17B10 | |
| SCHEMBL7431607 | 0.82 | ALDH1A1 (0.59) | ALDH1A1MAPTSTAT6TP53HSD17B10 | |
| SCHEMBL17327996 | 0.82 | ALDH1A1 (0.73) | ALDH1A1MAPTSTAT6TP53HSD17B10 | |
| SCHEMBL26550411 | 0.81 | ALDH1A1 (0.55) | ALDH1A1MAPTSTAT6TP53HSD17B10 | |
| SCHEMBL26550168 | 0.81 | ALDH1A1 (0.59) | ALDH1A1MAPTSTAT6TP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |