Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | TNF | P01375 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18262723 | 0.82 | KMT2A (0.77) | L3MBTL1POLBKMT2ATNFALDH1A1 | |
| SCHEMBL18262720 | 0.82 | KMT2A (0.77) | L3MBTL1POLBKMT2ATNFALDH1A1 | |
| SCHEMBL6693790 | 0.80 | TNF (0.65) | L3MBTL1POLBKMT2ATNFALDH1A1 | |
| SCHEMBL31259790 | 0.79 | TNF (0.51) | POLBKMT2ATNFALDH1A1GAA | |
| SCHEMBL6260167 | 0.79 | TNF (0.53) | POLBKMT2ATNFALDH1A1GAA | |
| SCHEMBL31259808 | 0.78 | TNF (0.50) | KMT2ATNFALDH1A1GAAMEN1 | |
| SCHEMBL8534121 | 0.78 | TNF (0.49) | POLBKMT2ATNFALDH1A1GAA | |
| SCHEMBL2167750 | 0.77 | ALDH1A1 (0.64) | POLBKMT2ATNFALDH1A1GAA | |
| SCHEMBL15930057 | 0.77 | ALDH1A1 (0.64) | POLBKMT2ATNFALDH1A1GAA | |
| SCHEMBL6255431 | 0.77 | TNF (0.53) | KMT2ATNFALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706521-A1 | NOVEL IMIDES | CELGENE CORPORATION (US) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001348-A2 | IMIDES AS INHIBITORS OF TNP ALPHA | CELGENE CORPORATION (US) | 1995-01-12 | — | — | WO | disclosed |