Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6268629 | 0.89 | ALDH1A1 (0.54) | TNFALDH1A1MAPK1KDM4ETP53 | |
| SCHEMBL2167750 | 0.86 | ALDH1A1 (0.64) | TNFALDH1A1MAPK1KDM4ETP53 | |
| SCHEMBL15930057 | 0.86 | ALDH1A1 (0.64) | TNFALDH1A1MAPK1KDM4ETP53 | |
| SCHEMBL2282582 | 0.84 | MEN1 (0.54) | TNFALDH1A1MAPK1KDM4ETP53 | |
| SCHEMBL2282489 | 0.84 | MEN1 (0.54) | TNFALDH1A1MAPK1KDM4ETP53 | |
| SCHEMBL29790477 | 0.84 | MEN1 (0.54) | TNFALDH1A1MAPK1KDM4ETP53 | |
| SCHEMBL2168623 | 0.84 | MEN1 (0.54) | TNFALDH1A1MAPK1KDM4ETP53 | |
| SCHEMBL31259790 | 0.84 | TNF (0.51) | TNFALDH1A1MAPK1KDM4ETP53 | |
| SCHEMBL6260167 | 0.83 | TNF (0.53) | TNFALDH1A1MAPK1KDM4ETP53 | |
| SCHEMBL31259808 | 0.83 | TNF (0.50) | TNFALDH1A1MAPK1ATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0847991-A1 | Method for the preparation of N-(carboxyalkyl) imides | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1998-06-17 | — | — | EP | disclosed |