Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FCER2 | P06734 | 4/20 | 0.62 |
| ▸ | MMP1 | P03956 | 2/20 | 0.62 |
| ▸ | REN | P00797 | 2/20 | 0.60 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.57 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.56 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.56 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | MME | P08473 | 1/20 | 0.54 |
| ▸ | NPY4R | P50391 | 2/20 | 0.54 |
| ▸ | NPY1R | P25929 | 1/20 | 0.54 |
| ▸ | NPY2R | P49146 | 1/20 | 0.54 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7591633 | 0.96 | FCER2 (0.66) | FCER2MMP1RENERAP2ERAP1 | |
| SCHEMBL2184039 | 0.96 | FCER2 (0.66) | FCER2MMP1RENERAP2ERAP1 | |
| Hydrochloric Acid SCHEMBL7294265 | 0.95 | FCER2 (0.65) | FCER2MMP1RENERAP2ERAP1 | |
| Hydrochloric Acid SCHEMBL7294268 | 0.95 | FCER2 (0.65) | FCER2MMP1RENERAP2ERAP1 | |
| SCHEMBL1913895 | 0.93 | BACE1 (0.57) | FCER2MMP1REN | |
| SCHEMBL5177480 | 0.91 | FCER2 (0.61) | FCER2MMP1KISS1RERAP2ERAP1 | |
| SCHEMBL30050978 | 0.91 | LTA4H (0.63) | LTA4HMME | |
| Hydrochloric Acid SCHEMBL9787692 | 0.90 | FCER2 (0.60) | FCER2MMP1RENERAP2ERAP1 | |
| SCHEMBL30573682 | 0.90 | FCER2 (0.59) | FCER2MMP1RENKISS1RLTA4H | |
| SCHEMBL17132263 | 0.90 | FCER2 (0.59) | FCER2MMP1RENKISS1RLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4771037-A | N-CARBOXYALKYL-PEPTIDES USEFUL AS INHIBITORS OF PROTEOGLYCANASE | ICI AMERICAS INC. (US) | 1988-09-13 | — | — | US | disclosed |