Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FCER2 | P06734 | 7/20 | 0.66 |
| ▸ | MMP1 | P03956 | 5/20 | 0.66 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.59 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.59 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.59 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | REN | P00797 | 1/20 | 0.54 |
| ▸ | MME | P08473 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP3 | P08254 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2184039 | 1.00 | FCER2 (0.66) | FCER2MMP1ERAP2ERAP1LNPEP | |
| Hydrochloric Acid SCHEMBL7294268 | 0.99 | FCER2 (0.65) | FCER2MMP1ERAP2ERAP1LNPEP | |
| Hydrochloric Acid SCHEMBL7294265 | 0.99 | FCER2 (0.65) | FCER2MMP1ERAP2ERAP1LNPEP | |
| SCHEMBL7436799 | 0.96 | FCER2 (0.62) | FCER2MMP1ERAP2ERAP1LNPEP | |
| SCHEMBL5177480 | 0.93 | FCER2 (0.61) | FCER2MMP1ERAP2ERAP1LNPEP | |
| SCHEMBL7323888 | 0.93 | FCER2 (0.58) | FCER2MMP1ERAP2ERAP1LNPEP | |
| Hydrochloric Acid SCHEMBL9787692 | 0.92 | FCER2 (0.60) | FCER2MMP1ERAP2ERAP1LNPEP | |
| Urea SCHEMBL28230423 | 0.90 | LTA4H (0.61) | LTA4HMMEMMP2 | |
| SCHEMBL29519583 | 0.90 | LTA4H (0.64) | LTA4HMMEMMP2 | |
| SCHEMBL2185269 | 0.90 | LTA4H (0.64) | LTA4HMMEMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108047304-A | - 7 selective depressant of metalloproteinases and its preparation method and application | 延边大学 | 2018-05-18 | — | — | CN | disclosed |
| EP-0769025-B1 | DIAGNOSTIC METHODS AND COMPOSITIONS RELATING TO THE PROTEOGLYCAN PROTEINS OF CARTILAGE BREAKDOWN | UNIV MELBOURNE (AU) | 2002-10-09 | — | — | EP | disclosed |
| US-5935796-A | Diagnostic methods and compositions relating to the proteoglycan proteins of cartilage breakdown | THE UNIVERSITY OF MELBOURNE (AU) | 1999-08-10 | — | — | US | disclosed |
| EP-0769025-A4 | DIAGNOSTIC METHODS AND COMPOSITIONS RELATING TO THE PROTEOGLYCAN PROTEINS OF CARTILAGE BREAKDOWN | UNIV MELBOURNE (AU) | 1999-06-16 | — | — | EP | disclosed |
| EP-0769025-A1 | DIAGNOSTIC METHODS AND COMPOSITIONS RELATING TO THE PROTEOGLYCAN PROTEINS OF CARTILAGE BREAKDOWN | THE UNIVERSITY OF MELBOURNE (AU) | 1997-04-23 | — | — | EP | disclosed |
| WO-1996001847-A1 | DIAGNOSTIC METHODS AND COMPOSITIONS RELATING TO THE PROTEOGLYCAN PROTEINS OF CARTILAGE BREAKDOWN | THE UNIVERSITY OF MELBOURNE (AU) | 1996-01-25 | — | — | WO | disclosed |