Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 8/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440014 | 0.92 | — | — | |
| SCHEMBL5843381 | 0.83 | CRHR1 (0.34) | CRHR1ALDH1A1KDM4ERAB9A | |
| SCHEMBL7436842 | 0.81 | CRHR1 (0.43) | CRHR1ALOX15 | |
| SCHEMBL6303126 | 0.79 | KDM4E (0.33) | CRHR1ALDH1A1KDM4ERAB9AMAPT | |
| SCHEMBL7429966 | 0.75 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL5599412 | 0.74 | CRHR1 (0.51) | CRHR1TDP1 | |
| SCHEMBL7440000 | 0.74 | CRHR1 (0.36) | CRHR1ALOX15 | |
| SCHEMBL7437868 | 0.74 | CRHR1 (0.36) | CRHR1ALOX15 | |
| SCHEMBL16450894 | 0.70 | ALDH1A1 (0.38) | ALDH1A1KDM4ERAB9ATSHRMAPT | |
| SCHEMBL6797092 | 0.68 | CRHR1 (0.50) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149583-A2 | Combinations of corticotropin releasing factor antagonists and growth hormone secretagogues | Pfizer Products Inc. (US) | 2001-10-31 | — | — | EP | claimed |