Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.50 |
| ▸ | METAP2 | P50579 | 3/20 | 0.44 |
| ▸ | METAP1 | P53582 | 2/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | CPN1 | P15169 | 2/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436910 | 1.00 | REN (0.50) | RENMETAP2METAP1SLC1A3SLC1A2 | |
| SCHEMBL9697153 | 0.88 | REN (0.46) | RENMETAP2METAP1SLC1A3SLC1A2 | |
| SCHEMBL10353656 | 0.83 | GRIK1 (0.51) | RENMETAP2METAP1SLC1A3SLC1A2 | |
| SCHEMBL4065186 | 0.82 | REN (0.55) | RENMETAP2METAP1ALDH1A1KMT2A | |
| SCHEMBL31109145 | 0.81 | CPN1 (0.47) | METAP2METAP1SLC1A3SLC1A2SLC1A1 | |
| Hydrochloric Acid SCHEMBL7360375 | 0.81 | REN (0.54) | RENMETAP2METAP1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL27673691 | 0.81 | REN (0.54) | RENMETAP2METAP1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL10676905 | 0.81 | REN (0.54) | RENMETAP2METAP1ALDH1A1KMT2A | |
| SCHEMBL8894601 | 0.80 | MME (0.43) | RENMETAP2METAP1SLC1A3SLC1A2 | |
| SCHEMBL8894607 | 0.80 | MME (0.43) | RENMETAP2METAP1SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0618222-A2 | Dipeptid derivatives of 5-amino-4-hydroxy-hexanoic acid | CIBA-GEIGY AG (CH) | 1994-10-05 | — | — | EP | disclosed |
| EP-0532466-A2 | Derivatives of 5-amino-4-hydroxy-hexanoic acid and their therapeutical use | CIBA-GEIGY AG (CH) | 1993-03-17 | — | — | EP | disclosed |