Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 4/20 | 0.43 |
| ▸ | METAP1 | P53582 | 4/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 4/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.38 |
| ▸ | LAP3 | P28838 | 1/20 | 0.38 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894607 | 1.00 | MME (0.43) | MMESLC7A5METAP2METAP1SLC1A3 | |
| SCHEMBL7430623 | 0.89 | METAP2 (0.45) | MMEMETAP2METAP1SLC1A3SLC1A2 | |
| SCHEMBL7430616 | 0.89 | METAP2 (0.45) | MMEMETAP2METAP1SLC1A3SLC1A2 | |
| SCHEMBL7433904 | 0.86 | LDHA (0.45) | METAP2METAP1RENPPARGANPEP | |
| SCHEMBL7436183 | 0.86 | EPHX1 (0.42) | MMEMETAP2METAP1SLC1A3SLC1A2 | |
| SCHEMBL7444337 | 0.86 | DPEP1 (0.44) | MMEMETAP2METAP1SLC1A3SLC1A2 | |
| SCHEMBL7433911 | 0.86 | LDHA (0.45) | METAP2METAP1RENPPARGANPEP | |
| SCHEMBL7444348 | 0.86 | DPEP1 (0.44) | MMEMETAP2METAP1SLC1A3SLC1A2 | |
| SCHEMBL7436178 | 0.86 | EPHX1 (0.42) | MMEMETAP2METAP1SLC1A3SLC1A2 | |
| SCHEMBL7436920 | 0.82 | SLC7A5 (0.56) | MMESLC7A5SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0618222-A2 | Dipeptid derivatives of 5-amino-4-hydroxy-hexanoic acid | CIBA-GEIGY AG (CH) | 1994-10-05 | — | — | EP | disclosed |