Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 15/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440251 | 0.89 | KDM4E (0.53) | KDM4EPKMGPR119NPC1RAB9A | |
| SCHEMBL7444156 | 0.83 | GPR119 (0.49) | KDM4EPKMGPR119 | |
| SCHEMBL24664329 | 0.82 | KDM4E (0.60) | KDM4EPKMGPR119 | |
| SCHEMBL12736012 | 0.81 | KDM4E (0.54) | KDM4EPKMGPR119KMT2AALDH1A1 | |
| SCHEMBL5663801 | 0.80 | ESR2 (0.57) | PKMGPR119NPC1RAB9AKMT2A | |
| SCHEMBL3907013 | 0.79 | KDM4E (0.55) | KDM4EPKMGPR119KMT2AALDH1A1 | |
| SCHEMBL1532753 | 0.79 | KDM4E (0.55) | KDM4EPKMGPR119 | |
| SCHEMBL7495311 | 0.79 | GPR119 (0.53) | KDM4EPKMGPR119KMT2A | |
| SCHEMBL7402974 | 0.79 | GPR119 (0.64) | KDM4EPKMGPR119ALDH1A1 | |
| SCHEMBL1575763 | 0.78 | KDM4E (0.49) | KDM4EPKMGPR119KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525617-A | ANTICOAGULANT | MERCK & CO., INC. (US) | 1996-06-11 | — | — | US | disclosed |