Sugi Predict

Sugi Predict / Compounds / SCHEMBL3907013

SCHEMBL3907013

SCHEMBL3907013

COC(=O)c1ccc(CC2CCN(C(=O)OC(C)(C)C)CC2)cc1

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.55
▸ PKM P14618 1/20 0.55
▸ HDAC1 Q13547 1/20 0.51
▸ HDAC6 Q9UBN7 1/20 0.51
▸ GPR119 Q8TDV5 10/20 0.50
▸ KMT2A Q03164 1/20 0.49
▸ TP53 P04637 1/20 0.48
▸ MAPT P10636 1/20 0.48
▸ THRB P10828 1/20 0.48
▸ ALDH1A1 P00352 1/20 0.48
▸ PTPN2 P17706 1/20 0.47
▸ PTPN1 P18031 1/20 0.47
▸ PTPN6 P29350 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12736012 0.89 KDM4E (0.54) KDM4EPKMHDAC1HDAC6GPR119
SCHEMBL6705316 0.88 L3MBTL1 (0.51) KDM4EPKMGPR119KMT2ATP53
SCHEMBL1252952 0.88 KDM4E (0.57) KDM4EPKMGPR119KMT2ATP53
SCHEMBL29136138 0.87 KMT2A (0.49) KDM4EHDAC1HDAC6KMT2A
SCHEMBL7495311 0.87 GPR119 (0.53) KDM4EPKMHDAC1HDAC6GPR119
SCHEMBL13717007 0.86 KDM4E (0.53) KDM4EPKMGPR119KMT2ATP53
SCHEMBL1575346 0.86 GPR119 (0.55) KDM4EPKMHDAC1HDAC6GPR119
SCHEMBL17982809 0.86 KDM4E (0.56) KDM4EPKMGPR119TP53MAPT
SCHEMBL28169019 0.85 ALDH1A1 (0.62) KDM4EPKMGPR119KMT2ATP53
SCHEMBL2250178 0.85 GPR119 (0.60) KDM4EPKMGPR119TP53ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4719384-A2 COMPOUNDS WITH ANTIFUNGAL PROPERTIES Trustees of Dartmouth College (US) 2026-04-08 — — EP disclosed
WO-2025262297-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 DARK BLUE THERAPEUTICS LTD (GB) 2025-12-26 — — WO disclosed
EP-4667467-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 Dark Blue Therapeutics Ltd (GB) 2025-12-24 — — EP disclosed
WO-2024249290-A2 COMPOUNDS WITH ANTIFUNGAL PROPERTIES TRUSTEES OF DARTMOUTH COLLEGE (US) 2024-12-05 — — WO disclosed
WO-2024173646-A1 CYCLIN-DEPENDENT KINASE DEGRADING COMPOUNDS INNOVO THERAPEUTICS, INC. (US) 2024-08-22 — — WO disclosed
CN-117586253-A Protein degradation agent, preparation method thereof and application thereof in pharmacy 上海汇伦医药股份有限公司 2024-02-23 — — CN disclosed
US-20230348389-A1 PIPERIDINE DERIVATIVES AS HDAC1/2 INHIBITORS REGENACY PHARMACEUTICALS LLC (US) 2023-11-02 — — US disclosed
US-20230250106-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY NOVARTIS PHARMA AG (CH) 2023-08-10 — — US disclosed
US-20230250106-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY NOVARTIS PHARMA AG (CH) 2023-08-10 — — US disclosed
US-20230250106-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY NOVARTIS PHARMA AG (CH) 2023-08-10 — — US disclosed
US-11702389-B2 Piperidine derivatives as HDAC1/2 inhibitors REGENACY PHARMACEUTICALS, LLC (US) 2023-07-18 — — US disclosed
WO-2022015977-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY IFM DUE, INC. (US) 2022-01-20 — — WO disclosed
CN-113454086-A Imidazo [2,1-F ] [1,2,4] triazin-4-amine derivatives as TLR7 agonists 百济神州有限公司 2021-09-28 — — CN disclosed
US-20180022702-A1 PIPERIDINE DERIVATIVES AS HDAC1/2 INHIBITORS ACETYLON PHARMACEUTICALS, INC. 2018-01-25 — — US disclosed
US-20170369441-A1 PIPERIDINE DERIVATIVES AS HDAC1/2 INHIBITORS REGENACY PHARMACEUTICALS, LLC 2017-12-28 — — US disclosed
US-9790180-B2 Piperidine derivatives as HDAC1/2 inhibitors REGENACY PHARMACEUTICALS, LLC (US) 2017-10-17 — — US disclosed
US-20160168093-A1 PIPERIDINE DERIVATIVES AS HDAC1/2 INHIBITORS REGENACY PHARMACEUTICALS, LLC 2016-06-16 — — US disclosed
EP-0976722-B1 BENZAMIDINE DERIVATIVES AJINOMOTO KK (JP) 2009-03-11 — — EP disclosed
US-7396844-B1 Benzamidine derivatives AJINOMOTO CO., INC. (JP) 2008-07-08 — — US disclosed
EP-0976722-A1 BENZAMIDINE DERIVATIVES Ajinomoto Co., Inc. (JP) 2000-02-02 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160168093-A1 PIPERIDINE DERIVATIVES AS HDAC1/2 INHIBITORS HDAC1, HDAC2, HDAC10 KDM4E 659/4885PKM 1937/4885HDAC1 1/4885
US-20170369441-A1 PIPERIDINE DERIVATIVES AS HDAC1/2 INHIBITORS HDAC1, HDAC2, HDAC10 KDM4E 659/4885PKM 1937/4885HDAC1 1/4885
US-11702389-B2 Piperidine derivatives as HDAC1/2 inhibitors HDAC1, HDAC2, HDAC10 KDM4E 659/4885PKM 1937/4885HDAC1 1/4885
US-20230250106-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY STING1, CGAS, IRF3 KDM4E 3761/4885PKM 3505/4885HDAC1 2416/4885
US-20230348389-A1 PIPERIDINE DERIVATIVES AS HDAC1/2 INHIBITORS HDAC1, HDAC2, HDAC10 KDM4E 659/4885PKM 1937/4885HDAC1 1/4885
US-20180022702-A1 PIPERIDINE DERIVATIVES AS HDAC1/2 INHIBITORS HDAC1, HDAC2, HDAC10 KDM4E 659/4885PKM 1937/4885HDAC1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.