Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.62 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23464917 | 0.85 | CHRM5 (0.75) | CHRM5CHRM3ALDH1A1TDP1KDM4E | |
| SCHEMBL18743787 | 0.83 | CHRM5 (0.72) | CHRM5CHRM3ALDH1A1TDP1KDM4E | |
| SCHEMBL7721235 | 0.83 | CHRM5 (0.72) | CHRM5CHRM3ALDH1A1TDP1KDM4E | |
| SCHEMBL25761251 | 0.81 | CHRM5 (0.53) | CHRM5CHRM3ALDH1A1TDP1KDM4E | |
| SCHEMBL13417680 | 0.81 | CHRM5 (0.70) | CHRM5CHRM3ALDH1A1TDP1KDM4E | |
| SCHEMBL7441593 | 0.79 | ALDH1A1 (0.38) | CHRM5CHRM3ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL18811738 | 0.78 | CHRM5 (0.66) | CHRM5CHRM3ALDH1A1TDP1KDM4E | |
| SCHEMBL2629206 | 0.78 | SIGMAR1 (0.66) | CHRM5CHRM3ALDH1A1TDP1KDM4E | |
| SCHEMBL20328825 | 0.78 | CHRM5 (0.66) | CHRM5CHRM3ALDH1A1TDP1KDM4E | |
| SCHEMBL18811886 | 0.78 | CHRM5 (0.66) | CHRM5CHRM3ALDH1A1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |