Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL334924 | 0.87 | KDM4E (0.56) | ALDH1A1KDM4EHSD17B10TSHRMAPT | |
| SCHEMBL7056764 | 0.74 | HPGD (0.59) | ALDH1A1KDM4EHSD17B10TSHRMAPT | |
| SCHEMBL12206768 | 0.73 | HSD17B2 (0.50) | ALDH1A1KDM4EHSD17B10TSHRMAPT | |
| SCHEMBL2894413 | 0.73 | HTT (0.46) | ALDH1A1KDM4EHSD17B10TSHRMAPT | |
| SCHEMBL24011663 | 0.73 | HTT (0.46) | ALDH1A1KDM4EHSD17B10TSHRMAPT | |
| SCHEMBL29625195 | 0.72 | KMT2A (0.58) | ALDH1A1KDM4EHSD17B10TSHRMAPT | |
| SCHEMBL222176 | 0.72 | KMT2A (0.58) | ALDH1A1KDM4EHSD17B10TSHRMAPT | |
| SCHEMBL10945617 | 0.71 | KMT2A (0.53) | ALDH1A1KDM4EHSD17B10TSHRMAPT | |
| SCHEMBL16887651 | 0.71 | KMT2A (0.53) | ALDH1A1KDM4EHSD17B10TSHRMAPT | |
| SCHEMBL2553110 | 0.71 | KMT2A (0.53) | ALDH1A1KDM4EHSD17B10TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4745118-A | BRONCHODILATOR AGENTS, CARDIOTONIC AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1988-05-17 | — | — | US | disclosed |