Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312054 | 0.88 | AGTR1 (0.49) | ACHEAGTR1AGTR2 | |
| SCHEMBL7302962 | 0.88 | PPARG (0.51) | ACHEAGTR1AGTR2 | |
| SCHEMBL7308657 | 0.87 | AGTR1 (0.48) | ACHEAGTR1AGTR2 | |
| SCHEMBL7435036 | 0.84 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL7308590 | 0.82 | PPARG (0.51) | ACHEAGTR1AGTR2 | |
| SCHEMBL7308525 | 0.82 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL7304962 | 0.82 | ACHE (0.49) | ACHEAGTR1AGTR2 | |
| SCHEMBL7304547 | 0.82 | ACHE (0.50) | ACHEAGTR1AGTR2 | |
| SCHEMBL7301439 | 0.82 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL7300759 | 0.81 | PPARG (0.52) | ACHEAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503785-B1 | 1-Biphenylimidazole derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 2001-04-25 | — | — | EP | disclosed |