Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | UBE2M | P61081 | 1/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10993611 | 0.90 | IDO1 (0.40) | LMNASMN1; SMN2TSHRMAPTNPSR1 | |
| SCHEMBL7437302 | 0.85 | TEAD1 (0.35) | — | |
| SCHEMBL7438128 | 0.84 | POLB (0.42) | LMNASMN1; SMN2MAPTNPSR1ALDH1A1 | |
| SCHEMBL7436242 | 0.84 | LMNA (0.46) | LMNASMN1; SMN2TSHRMAPTNPSR1 | |
| SCHEMBL7430181 | 0.81 | POLB (0.48) | LMNASMN1; SMN2TSHRMAPTNPSR1 | |
| SCHEMBL7441222 | 0.81 | CYP2D6 (0.36) | LMNASMN1; SMN2NPSR1ALDH1A1L3MBTL1 | |
| SCHEMBL7438351 | 0.80 | ALDH1A1 (0.40) | LMNATSHRNPSR1ALDH1A1L3MBTL1 | |
| SCHEMBL7445848 | 0.78 | POLB (0.45) | LMNASMN1; SMN2MAPTNPSR1ALDH1A1 | |
| SCHEMBL7442150 | 0.78 | DRD4 (0.52) | LMNASMN1; SMN2TSHRMAPTALDH1A1 | |
| SCHEMBL7495736 | 0.77 | TSHR (0.49) | LMNATSHRMAPTNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |