Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | ITK | Q08881 | 4/20 | 0.35 |
| ▸ | TXK | P42681 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.34 |
| ▸ | NTRK2 | Q16620 | 3/20 | 0.34 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436191 | 0.89 | F2 (0.44) | F2ITKTXKALDH1A1NTRK1 | |
| SCHEMBL7115169 | 0.86 | F2 (0.42) | F2ITKTXKALDH1A1NTRK1 | |
| SCHEMBL7120171 | 0.81 | HDAC1 (0.43) | F2ITKTXKNTRK1NTRK2 | |
| Hydrochloric Acid SCHEMBL7427082 | 0.79 | F2 (0.59) | F2 | |
| SCHEMBL7117041 | 0.77 | KCNH2 (0.41) | F2ITKALDH1A1NTRK1NTRK2 | |
| SCHEMBL7116629 | 0.76 | ITK (0.38) | F2ITKALDH1A1ACSL1HDAC1 | |
| Hydrochloric Acid SCHEMBL7438891 | 0.75 | F2 (0.57) | F2 | |
| Hydrochloric Acid SCHEMBL7437071 | 0.75 | F2 (0.56) | F2 | |
| SCHEMBL7217499 | 0.74 | F2 (0.42) | F2ALDH1A1ACSL1HDAC1HDAC8 | |
| Hydrochloric Acid SCHEMBL7436811 | 0.74 | F2 (0.56) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407130-B1 | ANTIALLERGENS, ANTIINFLAMMATORY AND ANTIARTHRITIC AGENTS; RESPIRATORY SYSTEM, GASTROINTESTINAL DISORDERS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-06-18 | — | — | US | disclosed |