Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 8/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | ITK | Q08881 | 3/20 | 0.39 |
| ▸ | TXK | P42681 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.37 |
| ▸ | NTRK2 | Q16620 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7124405 | 0.88 | F2 (0.57) | HDAC1HDAC8F2HDAC6 | |
| SCHEMBL7436191 | 0.87 | F2 (0.44) | HDAC1HDAC8F2HDAC6ITK | |
| SCHEMBL7115169 | 0.87 | F2 (0.42) | HDAC1HDAC8F2HDAC6ITK | |
| SCHEMBL7437334 | 0.81 | F2 (0.41) | HDAC1HDAC8F2ITKTXK | |
| SCHEMBL7117041 | 0.81 | KCNH2 (0.41) | HDAC1F2ITKRAB9ANTRK1 | |
| Hydrochloric Acid SCHEMBL7441346 | 0.79 | F2 (0.54) | HDAC1F2HDAC6 | |
| SCHEMBL7224825 | 0.79 | F2 (0.57) | F2NTRK1NTRK2 | |
| SCHEMBL8026604 | 0.78 | F2 (0.47) | HDAC1F2HDAC6ITKTXK | |
| Hydrochloric Acid SCHEMBL7440902 | 0.78 | F2 (0.54) | HDAC1F2HDAC6 | |
| SCHEMBL6160686 | 0.77 | NPC1 (0.44) | HDAC1HDAC8F2RAB9ANTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6656956-B2 | Tryptase inhibitor; antiinflamamtory agents, antiallergens | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-12-02 | — | — | US | disclosed |
| US-20030105137-A1 | Benzimidazole derivatives, processes for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105137-A1 | Benzimidazole derivatives, processes for preparing them and their use as pharmaceutical compositions | CMA1, TPSD1, TPSAB1 | HDAC1 240/4885HDAC8 390/4885F2 764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.