Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | HPN | P05981 | 3/20 | 0.48 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.48 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7432546 | 0.90 | PLAU (0.55) | PLAUKMT2AAIMP2MEN1F2 | |
| SCHEMBL7436288 | 0.87 | F2 (0.54) | PLAUKMT2AAIMP2MEN1F2 | |
| Hydrochloric Acid SCHEMBL7497049 | 0.86 | F2 (0.53) | PLAUKMT2AAIMP2MEN1F2 | |
| SCHEMBL29704561 | 0.77 | PLG (0.77) | PLAUF2HPNST14HGFAC | |
| Hydrochloric Acid SCHEMBL7441720 | 0.76 | PLAU (0.57) | PLAUKMT2AAIMP2MEN1F2 | |
| SCHEMBL7445799 | 0.76 | PLAU (0.55) | PLAUKMT2AAIMP2MEN1F2 | |
| SCHEMBL9753026 | 0.73 | POLB (0.62) | PLAUKMT2AAIMP2MEN1NPC1 | |
| SCHEMBL22501273 | 0.70 | KMT2A (0.77) | PLAUKMT2AAIMP2MEN1F2 | |
| SCHEMBL30964136 | 0.70 | KMT2A (0.77) | PLAUKMT2AAIMP2MEN1F2 | |
| SCHEMBL7441859 | 0.69 | PLAU (0.50) | PLAUKMT2AAIMP2MEN1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5248673-A | Antiischemic, anticoagulant | BRISTOL-MYERS SQUIBB CO. (US) | 1993-09-28 | — | — | US | claimed |