Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.52 |
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436288 | 0.88 | F2 (0.54) | PLAUF2KMT2AMEN1AIMP2 | |
| Hydrochloric Acid SCHEMBL7497049 | 0.87 | F2 (0.53) | PLAUF2KMT2AMEN1AIMP2 | |
| Hydrochloric Acid SCHEMBL7441720 | 0.85 | PLAU (0.57) | PLAUF2KMT2AMEN1AIMP2 | |
| SCHEMBL7432546 | 0.81 | PLAU (0.55) | PLAUF2KMT2AMEN1AIMP2 | |
| SCHEMBL7431293 | 0.80 | PLAU (0.49) | PLAUF2KMT2AMEN1AIMP2 | |
| SCHEMBL7441859 | 0.78 | PLAU (0.50) | PLAUF2KMT2AMEN1AIMP2 | |
| SCHEMBL8660702 | 0.76 | F2 (0.58) | PLAUF2 | |
| SCHEMBL7437350 | 0.76 | PLAU (0.56) | PLAUF2KMT2AMEN1AIMP2 | |
| SCHEMBL9753026 | 0.74 | POLB (0.62) | PLAUKMT2AMEN1AIMP2NPC1 | |
| SCHEMBL22501264 | 0.71 | KMT2A (0.74) | F2KMT2AMEN1AIMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328932-A | Cardiovascular disorders, antiischemic agents and stroke | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-07-12 | — | — | US | disclosed |
| US-5248673-A | Antiischemic, anticoagulant | BRISTOL-MYERS SQUIBB CO. (US) | 1993-09-28 | — | — | US | disclosed |