SCHEMBL7436288

SCHEMBL7436288

Cc1ccc(S(=O)(=O)NC(CCCCNC(=N)C(=N)N)C(=O)N2CCCCC2)cc1

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
F2 P00734 4/20 0.54
PLAU P00749 2/20 0.52
ITGB3 P05106 1/20 0.48
ITGA2B P08514 1/20 0.48
AIMP2 Q13155 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
HPN P05981 3/20 0.47
ST14 Q9Y5Y6 2/20 0.47
TGM2 P21980 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.44
HGFAC Q04756 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7497049 0.99 F2 (0.53) F2PLAUITGB3ITGA2BAIMP2
SCHEMBL7432546 0.93 PLAU (0.55) F2PLAUAIMP2MEN1KMT2A
SCHEMBL7445799 0.88 PLAU (0.55) F2PLAUITGB3ITGA2BAIMP2
SCHEMBL7437350 0.87 PLAU (0.56) F2PLAUITGB3ITGA2BAIMP2
Hydrochloric Acid SCHEMBL7441720 0.82 PLAU (0.57) F2PLAUAIMP2MEN1KMT2A
SCHEMBL7431293 0.78 PLAU (0.49) F2PLAUAIMP2MEN1KMT2A
SCHEMBL7442385 0.76 F2 (0.67) F2
SCHEMBL7441859 0.75 PLAU (0.50) F2PLAUAIMP2MEN1KMT2A
Hydrochloric Acid SCHEMBL9337462 0.74 F2 (0.66) F2
SCHEMBL1244355 0.73 ITGB3 (0.60) PLAUITGB3ITGA2BHPN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5248673-A Antiischemic, anticoagulant BRISTOL-MYERS SQUIBB CO. (US) 1993-09-28 US claimed