Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440935 | 0.93 | CES2 (0.39) | CES1CES2ALDH1A1FFAR1TDP1 | |
| SCHEMBL7438751 | 0.91 | CES2 (0.41) | CES1CES2ALDH1A1FFAR1TDP1 | |
| SCHEMBL7389115 | 0.84 | CA2 (0.36) | CES1CES2ALDH1A1TDP1 | |
| SCHEMBL5967506 | 0.84 | CES1 (0.43) | CES1CES2ALDH1A1TP53CA1 | |
| SCHEMBL11302385 | 0.79 | CHRM1 (0.34) | CES1CES2ALDH1A1TP53FFAR1 | |
| SCHEMBL19329327 | 0.79 | CES2 (0.43) | CES1CES2ALDH1A1FFAR1TDP1 | |
| SCHEMBL8708258 | 0.79 | CES1 (0.39) | CES1CES2ALDH1A1TP53CA1 | |
| SCHEMBL10742718 | 0.79 | CES1 (0.39) | CES1CES2ALDH1A1TP53CA1 | |
| SCHEMBL9223712 | 0.76 | PAOX (0.38) | ALDH1A1CA1LMNAMEN1KMT2A | |
| SCHEMBL6079694 | 0.76 | CES2 (0.30) | CES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4771037-A | N-CARBOXYALKYL-PEPTIDES USEFUL AS INHIBITORS OF PROTEOGLYCANASE | ICI AMERICAS INC. (US) | 1988-09-13 | — | — | US | disclosed |