Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PPID | Q08752 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL783009 | 0.87 | CA2 (0.41) | GAAKMT2ACTSKMEN1 | |
| SCHEMBL15194399 | 0.85 | ALDH1A1 (0.49) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL753960 | 0.85 | ALDH1A1 (0.46) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL391332 | 0.85 | GAA (0.65) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL398900 | 0.84 | CA12 (0.46) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL7428662 | 0.83 | GAA (0.47) | GAAMGAMSIMGAM2CYP1A2 | |
| Hydrochloric Acid SCHEMBL27917473 | 0.83 | GAA (0.62) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL28234269 | 0.83 | GAA (0.62) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL15488645 | 0.82 | PTPRC (0.35) | GAAMAPT | |
| SCHEMBL223549 | 0.81 | GAA (0.68) | GAAMGAMSIMGAM2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |