Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444491 | 0.89 | CA2 (0.40) | CA2FFAR1ALDH1A1KMT2A | |
| SCHEMBL7434309 | 0.81 | CA2 (0.48) | CA2FFAR1AHRCA1 | |
| SCHEMBL2487394 | 0.81 | CA2 (0.48) | CA2FFAR1AHRCA1 | |
| SCHEMBL7443159 | 0.81 | CA2 (0.48) | CA2FFAR1AHRCA1 | |
| SCHEMBL7446435 | 0.80 | AHR (0.37) | AHR | |
| SCHEMBL7434642 | 0.76 | — | — | |
| SCHEMBL7436292 | 0.74 | CA2 (0.48) | CA2FFAR1KMT2A | |
| SCHEMBL7437340 | 0.74 | CA2 (0.42) | CA2KMT2A | |
| SCHEMBL1299611 | 0.73 | NISCH (0.44) | CA2HPGDALDH1A1 | |
| SCHEMBL1299583 | 0.73 | NISCH (0.44) | CA2HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4558129-A | Benzodioxanyl-hydroxyethylene-piperazinyl acetanilides which effect calcium entry and β-blockade | SYNTEX (U.S.A.) INC. (US) | 1985-12-10 | — | — | US | disclosed |
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |