Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434642 | 0.86 | — | — | |
| SCHEMBL7437647 | 0.80 | CA2 (0.44) | AHR | |
| SCHEMBL7446440 | 0.74 | GAA (0.37) | AHR | |
| SCHEMBL7444491 | 0.73 | CA2 (0.40) | — | |
| SCHEMBL7432845 | 0.73 | LMNA (0.35) | — | |
| SCHEMBL2524829 | 0.71 | CA2 (0.49) | AHR | |
| SCHEMBL7434309 | 0.69 | CA2 (0.48) | AHR | |
| SCHEMBL2487394 | 0.69 | CA2 (0.48) | AHR | |
| SCHEMBL7438079 | 0.68 | — | — | |
| SCHEMBL7436351 | 0.66 | AHR (0.33) | AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4558129-A | Benzodioxanyl-hydroxyethylene-piperazinyl acetanilides which effect calcium entry and β-blockade | SYNTEX (U.S.A.) INC. (US) | 1985-12-10 | — | — | US | disclosed |
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |