Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.59 |
| ▸ | MME | P08473 | 1/20 | 0.56 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10710869 | 1.00 | ACE (0.59) | ACEMMEMMEL1 | |
| SCHEMBL7432306 | 0.89 | HRH4 (0.54) | ACEMME | |
| SCHEMBL7432294 | 0.89 | HRH4 (0.54) | ACEMME | |
| SCHEMBL7444128 | 0.83 | ACE (0.67) | ACEMMEMMEL1 | |
| SCHEMBL7444122 | 0.83 | ACE (0.67) | ACEMMEMMEL1 | |
| SCHEMBL7383447 | 0.83 | ACE (0.46) | ACEMMEMMEL1 | |
| SCHEMBL7428482 | 0.82 | CYP1A2 (0.51) | — | |
| SCHEMBL7428489 | 0.82 | CYP1A2 (0.51) | — | |
| SCHEMBL7439441 | 0.81 | PRKCA (0.44) | MME | |
| SCHEMBL9622053 | 0.81 | PRKCA (0.44) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5096925-A | N-substituted butyramide derivatives | CIBA-GEIGY CORPORATION (US) | 1992-03-17 | — | — | US | disclosed |
| US-4939261-A | ANALGESICS, ANTIDEPRESSANTS, HYPOTENSIVE AGENTS, NEUROLEPTIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1990-07-03 | — | — | US | disclosed |
| EP-0185079-B1 | N-SUBSTITUTED BUTYRAMIDE DERIVATIVES | CIBA-GEIGY AG (CH) | 1988-10-19 | — | — | EP | disclosed |
| EP-0185079-A1 | — | CIBA GEIGY AG | 1986-06-25 | — | — | EP | disclosed |
| WO-1986000066-A1 | N-SUBSTITUTED BUTYRAMIDE DERIVATIVES | CIBA-GEIGY AG (CH) | 1986-01-03 | — | — | WO | disclosed |