Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.47 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.47 |
| ▸ | CPA1 | P15085 | 3/20 | 0.46 |
| ▸ | CPA3 | P15088 | 3/20 | 0.46 |
| ▸ | CPB1 | P15086 | 1/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.43 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7428482 | 1.00 | CYP1A2 (0.51) | CYP1A2SLC1A3SLC1A2SLC1A1FOLH1 | |
| SCHEMBL7439441 | 0.90 | PRKCA (0.44) | CYP1A2SLC1A3SLC1A2SLC1A1ANPEP | |
| SCHEMBL9622053 | 0.90 | PRKCA (0.44) | CYP1A2SLC1A3SLC1A2SLC1A1ANPEP | |
| SCHEMBL7435519 | 0.89 | CYP1A2 (0.41) | CYP1A2SLC1A3SLC1A2SLC1A1FOLH1 | |
| SCHEMBL7435528 | 0.89 | CYP1A2 (0.41) | CYP1A2SLC1A3SLC1A2SLC1A1FOLH1 | |
| SCHEMBL9622042 | 0.83 | MME (0.61) | — | |
| SCHEMBL7437675 | 0.82 | ACE (0.59) | — | |
| SCHEMBL10710869 | 0.82 | ACE (0.59) | — | |
| SCHEMBL6840431 | 0.80 | SLC7A5 (0.51) | SLC1A3SLC1A2SLC1A1ANPEPRNPEP | |
| SCHEMBL7432297 | 0.79 | SLC15A1 (0.52) | CYP1A2SLC1A3SLC1A2SLC1A1ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166212-A | Hypotensive agents, analgesics | CIBA-GEIGY CORPORATION (US) | 1992-11-24 | — | — | US | disclosed |
| US-5096925-A | N-substituted butyramide derivatives | CIBA-GEIGY CORPORATION (US) | 1992-03-17 | — | — | US | disclosed |
| US-5021430-A | Enkephalinase inhibitors, analgesics, hypotensives | CIBA-GEIGY CORPORATION (US) | 1991-06-04 | — | — | US | disclosed |
| US-4939261-A | ANALGESICS, ANTIDEPRESSANTS, HYPOTENSIVE AGENTS, NEUROLEPTIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1990-07-03 | — | — | US | disclosed |
| EP-0185079-A1 | — | CIBA GEIGY AG | 1986-06-25 | — | — | EP | disclosed |
| WO-1986000066-A1 | N-SUBSTITUTED BUTYRAMIDE DERIVATIVES | CIBA-GEIGY AG (CH) | 1986-01-03 | — | — | WO | disclosed |