Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.71 |
| ▸ | TSHR | P16473 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL27310497 | 0.89 | — | — | |
| Isopropyl Alcohol SCHEMBL10690908 | 0.89 | — | — | |
| Propylene Glycol SCHEMBL10707018 | 0.85 | — | — | |
| Propylene Glycol SCHEMBL161401 | 0.84 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNAL3MBTL1 | |
| Propylene Glycol SCHEMBL7522896 | 0.84 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNAL3MBTL1 | |
| Propylene Glycol SCHEMBL15864609 | 0.84 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNAL3MBTL1 | |
| Propylene Glycol SCHEMBL55583 | 0.84 | — | — | |
| Propylene Glycol SCHEMBL3535 | 0.84 | — | — | |
| Propylene Glycol SCHEMBL724028 | 0.84 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNAL3MBTL1 | |
| Propylene Glycol SCHEMBL28578 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5002776-A | Multilayer polymeric membrane | ELAN CORPORATION, PLC (IE) | 1991-03-26 | — | — | US | disclosed |