Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR142 | Q7Z601 | 8/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 2/20 | 0.41 |
| ▸ | CPA3 | P15088 | 2/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | CPB1 | P15086 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7280731 | 0.88 | CYP1A2 (0.61) | GPR142CYP1A2SLC6A3SLC1A3SLC1A2 | |
| SCHEMBL5052372 | 0.79 | CYP1A2 (0.68) | CYP1A2EPHX1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL9079440 | 0.79 | DPP4 (0.38) | GPR142SLC6A3CAPN1 | |
| SCHEMBL9079444 | 0.79 | DPP4 (0.38) | GPR142SLC6A3CAPN1 | |
| SCHEMBL7293701 | 0.79 | REN (0.48) | GPR142REN | |
| SCHEMBL5862043 | 0.78 | PTPRA (0.55) | CYP1A2EPHX1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL24533871 | 0.74 | CTSL (0.50) | GPR142 | |
| SCHEMBL5273058 | 0.73 | DPP4 (0.49) | GPR142SLC6A3CAPN1FOLH1 | |
| SCHEMBL7401594 | 0.73 | DPP4 (0.49) | GPR142SLC6A3CAPN1FOLH1 | |
| SCHEMBL5207691 | 0.73 | DPP4 (0.49) | GPR142SLC6A3CAPN1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416393-A1 | Peptidyl difluorodiol renin inhibitors | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |