Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 7/20 | 0.41 |
| ▸ | CTSS | P25774 | 6/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL939491 | 0.81 | PTPN11 (0.47) | PTPN11MEN1GAAKMT2ATDP1 | |
| SCHEMBL21410149 | 0.81 | PTPN11 (0.49) | PTPN11MEN1GAAKMT2ATDP1 | |
| SCHEMBL14404775 | 0.80 | CTSK (0.51) | PTPN11MEN1GAAKMT2ATDP1 | |
| SCHEMBL659104 | 0.80 | TDP1 (0.52) | PTPN11MEN1GAAKMT2ATDP1 | |
| SCHEMBL14085304 | 0.80 | PTPN11 (0.48) | PTPN11MEN1GAAKMT2ATDP1 | |
| SCHEMBL6623918 | 0.79 | MEN1 (0.38) | PTPN11MEN1GAAKMT2ATDP1 | |
| SCHEMBL31526439 | 0.79 | MEN1 (0.45) | PTPN11MEN1GAAKMT2ATDP1 | |
| SCHEMBL24094851 | 0.78 | PTPN11 (0.47) | PTPN11MEN1GAAKMT2ATDP1 | |
| SCHEMBL2143910 | 0.78 | PTPN11 (0.47) | PTPN11MEN1GAAKMT2ATDP1 | |
| SCHEMBL13306431 | 0.78 | PTPN11 (0.47) | PTPN11MEN1GAAKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995023811-A1 | NOVEL CARBOCYCLIC COMPOUNDS WHICH INHIBIT PLATELET AGGREGATION BY INTERACTION WITH THE GPIIB/IIIA RECEPTOR COMPLEX | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-09-08 | — | — | WO | disclosed |