SCHEMBL74379

SCHEMBL74379

O=C(Cl)c1ccc2c(c1)C(=O)OC2=O

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.49
CA7 P43166 5/20 0.49
CA1 P00915 4/20 0.49
CA4 P22748 2/20 0.49
CA2 P00918 2/20 0.49
CA9 Q16790 1/20 0.49
ALOX15 P16050 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ALDH1A1 P00352 2/20 0.43
MAPT P10636 1/20 0.42
MCL1 Q07820 1/20 0.42
TTR P02766 2/20 0.40
PTPRC P08575 2/20 0.39
TSHR P16473 1/20 0.38
S100A4 P26447 1/20 0.38
HSD17B10 Q99714 1/20 0.37
POLB P06746 1/20 0.37
KMT2A Q03164 1/20 0.37
TYMS P04818 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29490657 1.00 CA12 (0.49) CA12CA7CA1CA4CA2
SCHEMBL3695029 0.91 CA12 (0.50) CA12CA7CA1CA4CA2
Pyromellitic Acid SCHEMBL10536463 0.90 CA12 (0.56) CA12CA7CA1CA4CA2
Phenol SCHEMBL27471324 0.90 CA12 (0.52) CA12CA7CA1CA4CA2
SCHEMBL11629228 0.90 TDP1 (0.44) CA12CA7CA1CA4CA2
SCHEMBL9602971 0.89 CA12 (0.45) CA12CA7CA1CA4CA2
SCHEMBL23630427 0.85 CA12 (0.42) CA12CA7CA1CA4CA2
SCHEMBL29868120 0.85 CA12 (0.42) CA12CA7CA1CA4CA2
SCHEMBL21917632 0.85 CA12 (0.53) CA12CA7CA1CA4CA2
SCHEMBL169521 0.83 CA12 (0.51) CA12CA7CA1CA4CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5417 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250176537-A1 POLYESTER-POLYETHER SOLID ARTICLE COMPRISING PHEROMONE THE PROCTER & GAMBLE COMPANY 2025-06-05 US claimed
US-20250177597-A1 POLYESTER-POLYETHER SOLID ARTICLE COMPRISING HYDROPHOBIC MATERIAL THE PROCTER & GAMBLE COMPANY 2025-06-05 US claimed
CN-119931586-A Preparation method of polyamide imide-polyimide copolymer resin adhesive and semiconductor element temporary packaging adhesive film 芜湖徽氏新材料科技有限公司 2025-05-06 CN claimed
CN-114651031-B Reactive polyamideimide oligomers, methods, and articles 北卡罗来纳-查佩尔山大学 2025-02-25 CN claimed
CN-119390982-A Reactive oligomers, additive manufacturing methods, and articles thereof 北卡罗来纳-查佩尔山大学 2025-02-07 CN claimed
US-12187893-B2 Thermoplastic compositions, methods of their manufacture, and articles thereof SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2025-01-07 US claimed
CN-118991271-A Preparation method of quantum dot functional printing light guide plate 广东欧迪明光电科技股份有限公司 2024-11-22 CN claimed
CN-114829455-B Reactive oligomers, additive manufacturing methods, and articles thereof 北卡罗来纳-查佩尔山大学 2024-11-15 CN claimed
EP-3976706-B1 THERMOPLASTIC COMPOSITIONS, METHODS OF THEIR MANUFACTURE, AND ARTICLES THEREOF SHPP GLOBAL TECH BV (NL) 2024-11-06 EP claimed
WO-2023192255-A9 OPTICALLY TRANSPARENT POLYAMIDE-IMIDES ZYMERGEN INC. (US) 2024-10-24 WO claimed
US-5118765-A Heat resistant molding materials CHEMIE HOLDING AKTIENGESELLSCHAFT (AT) 1992-06-02 US claimed
EP-0473871-A2 Fluorine-containing compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1992-03-11 EP claimed
EP-0260709-B1 FUSIBLE AND SOLUBLE POLYAMIDEIMIDE-POLYIMIDE BLOCK POLYMERS Chemie Linz Gesellschaft m.b.H. (AT) 1991-07-24 EP claimed
EP-0368413-A2 Polyphenylene sulfide resin composition GE PLASTICS JAPAN LIMITED (JP) 1990-05-16 EP claimed
US-4886873-A ELASTICITY AND HEAT RESISTANCE DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1989-12-12 US claimed
EP-0227043-A2 Composite semipermeable membrane and process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-07-01 EP claimed
US-4331799-A HALOGORMYLPHTHALIC ANHYDRIDE, DIAMINE, AROMATIC DIOXYBIS/PHTHALIC ANHYDRIDE GENERAL ELECTRIC COMPANY (US) 1982-05-25 US claimed
US-4214071-A Amide-imide polymers WESTINGHOUSE ELECTRIC CORP. (US) 1980-07-22 US claimed
US-3984375-A Aromatic amide-imide polymers WESTINGHOUSE ELECTRIC CORPORATION (US) 1976-10-05 US claimed
US-3939029-A Method of bonding utilizing a heat activated polyamide adhesive STANDARD OIL COMPANY (US) 1976-02-17 US claimed