SCHEMBL23630427

SCHEMBL23630427

O=C(Cl)c1ccc(-c2ccc3c(c2)C(=O)OC3=O)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.42
CA7 P43166 5/20 0.42
CA1 P00915 4/20 0.42
CA2 P00918 2/20 0.42
CA9 Q16790 1/20 0.42
CA4 P22748 2/20 0.41
ALOX15 P16050 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 2/20 0.39
TDP2 O95551 4/20 0.38
MAPT P10636 2/20 0.37
MEN1 O00255 1/20 0.37
APAF1 O14727 1/20 0.37
NPC1 O15118 1/20 0.37
LMNA P02545 1/20 0.37
THRB P10828 1/20 0.37
XBP1 P17861 1/20 0.37
PTBP1 P26599 1/20 0.37
HTT P42858 1/20 0.37
RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29868120 1.00 CA12 (0.42) CA12CA7CA1CA2CA9
SCHEMBL29490657 0.85 CA12 (0.49) CA12CA7CA1CA2CA9
SCHEMBL74379 0.85 CA12 (0.49) CA12CA7CA1CA2CA9
SCHEMBL724251 0.84 TDP2 (0.53) CA12CA7CA1CA2CA9
SCHEMBL29366467 0.83 ALOX15 (0.55) CA12CA7CA1CA4ALOX15
SCHEMBL15641977 0.83 ALOX15 (0.55) CA12CA7CA1CA4ALOX15
SCHEMBL308376 0.83 ALOX15 (0.55) CA12CA7CA1CA4ALOX15
SCHEMBL17192488 0.83 ALOX15 (0.55) CA12CA7CA1CA4ALOX15
SCHEMBL9602971 0.83 CA12 (0.45) CA12CA7CA1CA2CA9
SCHEMBL741462 0.81 ALOX15 (0.57) CA12CA7CA1CA4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114929782-A Method for producing mixed polyamides, polyimides and polyamideimides by hydrothermal polymerization 埃克森美孚技术与工程公司 2022-08-19 CN claimed
WO-2021141807-A1 METHODS FOR PREPARING MIXED POLYAMIDES, POLYIMIDES AND POLYAMIDEIMlDES VIA HYDROTHERMAL POLYMERIZATION EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2021-07-15 WO claimed
EP-4087892-A1 METHODS FOR PREPARING MIXED POLYAMIDES, POLYIMIDES AND POLYAMIDEIMLDES VIA HYDROTHERMAL POLYMERIZATION ExxonMobil Technology and Engineering Company (US) 2022-11-16 EP disclosed
CN-114929782-A Method for producing mixed polyamides, polyimides and polyamideimides by hydrothermal polymerization 埃克森美孚技术与工程公司 2022-08-19 CN disclosed
WO-2021141807-A1 METHODS FOR PREPARING MIXED POLYAMIDES, POLYIMIDES AND POLYAMIDEIMlDES VIA HYDROTHERMAL POLYMERIZATION EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2021-07-15 WO disclosed