SCHEMBL9602971

SCHEMBL9602971

O=C(Cl)c1ccc(C(=O)c2ccc3c(c2)C(=O)OC3=O)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.45
CA7 P43166 5/20 0.45
CA1 P00915 4/20 0.45
CA2 P00918 2/20 0.45
CA9 Q16790 1/20 0.45
CA4 P22748 2/20 0.44
PTPRC P08575 3/20 0.40
TDP1 Q9NUW8 3/20 0.39
ALOX15 P16050 1/20 0.39
ALDH1A1 P00352 3/20 0.39
MAPT P10636 1/20 0.39
MCL1 Q07820 1/20 0.39
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ENPP2 Q13822 1/20 0.38
HSD17B1 P14061 1/20 0.38
HSD17B2 P37059 1/20 0.38
HPGD P15428 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
APEX1 P27695 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27356295 0.91 CA12 (0.50) CA12CA7CA1CA2CA9
SCHEMBL11629228 0.90 TDP1 (0.44) CA12CA7CA1CA2CA9
SCHEMBL74379 0.89 CA12 (0.49) CA12CA7CA1CA2CA9
SCHEMBL29490657 0.89 CA12 (0.49) CA12CA7CA1CA2CA9
SCHEMBL169521 0.89 CA12 (0.51) CA12CA7CA1CA2CA9
SCHEMBL9146656 0.86 CA12 (0.55) CA12CA7CA1CA2CA9
SCHEMBL1271059 0.86 TDP1 (0.55) CA12CA7CA1CA2CA9
SCHEMBL9062200 0.84 SRD5A2 (0.54) CA12CA7CA1CA2CA9
SCHEMBL432542 0.84 TDP1 (0.52) CA12CA7CA1CA2CA9
SCHEMBL23630427 0.83 CA12 (0.42) CA12CA7CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0315992-B1 SULFUR-CONTAINING AROMATIC TETRACARBOXYLIC ACIDS AND THEIR DERIVATIVES CHEMIE LINZ GMBH (AT) 1993-08-11 EP disclosed
US-5126462-A Monomers for soluble, fusible polyimides or polyamideimides CHEMIE LINZ GESELLSCHAFT M.B.H. (AT) 1992-06-30 US disclosed
EP-0315993-B1 SOLUBLE AND/OR FUSIBLE BLOCK POLYAMIDE-POLYAMIDES, POLYAMIDE-POLYAMIDEIMIDES AND POLYAMIDES-POLYIMIDES Chemie Linz Gesellschaft m.b.H. (AT) 1992-04-01 EP disclosed
EP-0390803-A1 SULFUR-CONTAINING AROMATIC TETRACARBOXYLIC ACIDS AND THEIR DERIVATIVES Chemie Linz Gesellschaft m.b.H. (AT) 1990-10-10 EP disclosed
WO-1989004298-A1 SULFUR-CONTAINING AROMATIC TETRACARBOXYLIC ACIDS AND THEIR DERIVATIVES CHEMIE LINZ GESELLSCHAFT M.B.H. (AT) 1989-05-18 WO disclosed
EP-0315992-A1 Sulfur-containing aromatic tetracarboxylic acids and their derivatives Chemie Linz Gesellschaft m.b.H. (AT) 1989-05-17 EP disclosed
EP-0315993-A1 Soluble and/or fusible block polyamide-polyamides, polyamide-polyamideimides and polyamides-polyimides Chemie Linz Gesellschaft m.b.H. (AT) 1989-05-17 EP disclosed