Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 2/20 | 0.55 |
| ▸ | WNT3A | P56704 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30313764 | 0.83 | CTNNB1 (0.71) | CTNNB1WNT3ATSHRMAPTMEN1 | |
| SCHEMBL6600362 | 0.83 | CTNNB1 (0.71) | CTNNB1WNT3ATSHRMAPTMEN1 | |
| SCHEMBL7437162 | 0.82 | MAPT (0.50) | CTNNB1WNT3ATSHRMAPTMEN1 | |
| SCHEMBL20245289 | 0.81 | HDAC1 (0.57) | MAPTPDE4BHDAC3HDAC2ALDH1A1 | |
| SCHEMBL7413883 | 0.80 | MAPT (0.55) | CTNNB1WNT3ATSHRMAPTMEN1 | |
| SCHEMBL27942039 | 0.79 | KMT2A (0.54) | MEN1KMT2ACYP1A2CYP2C19KDM4E | |
| SCHEMBL3652524 | 0.79 | MAPT (0.59) | CTNNB1WNT3ATSHRMAPTMEN1 | |
| SCHEMBL7439618 | 0.78 | MAPT (0.52) | CTNNB1WNT3ATSHRMAPTMEN1 | |
| SCHEMBL1659363 | 0.78 | MAPT (0.71) | CTNNB1WNT3ATSHRMAPTMEN1 | |
| SCHEMBL10455919 | 0.78 | CTNNB1 (0.83) | CTNNB1WNT3ATSHRMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4745118-A | BRONCHODILATOR AGENTS, CARDIOTONIC AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1988-05-17 | — | — | US | disclosed |